Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzenesulfonic Acid 2,2-Dimethylpropyl Ester is a high-value organoboron building block designed for advanced synthetic chemistry. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex aryl-aryl linkages.
• Materials Science: Precursor for creating advanced organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Enables the synthesis of bioconjugates and molecular probes for drug discovery and diagnostic applications.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts.
• Polymer Modification: Used to introduce functional arylboronate ester groups into polymer backbones for specialty materials.

Basic Information

Item	Detail
Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzenesulfonic Acid 2,2-Dimethylpropyl Ester
CAS No.	648905-68-4
Molecular Formula	C17H27BO5S
Molecular Weight	354.27 g/mol
Synonyms	Neopentyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonate; 2,2-Dimethylpropyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonate; 4-(Pinacolatoboryl)benzenesulfonic Acid Neopentyl Ester; 4-Boronic Acid Pinacol Ester Benzenesulfonic Acid Neopentyl Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl Neopentyl Sulfonate
EINECS	Contact for details

Quality Control

Our production of 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzenesulfonic Acid 2,2-Dimethylpropyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.