Description

4-(tert-Butylamino)Sulfonylphenylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl bond formations.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and semiconductors, where precise molecular structure is paramount.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel palladium catalyst ligands and other organometallic complexes.
• Custom Synthesis & Contract Manufacturing: An important reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(tert-Butylamino)Sulfonylphenylboronic Acid Pinacol Ester
CAS No.	648905-63-9
Molecular Formula	C₁₆H₂₆BNO₄S
Molecular Weight	339.26 g/mol
Synonyms	4-[(tert-Butylamino)sulfonyl]benzeneboronic Acid Pinacol Ester; 4-(N-tert-Butylsulfamoyl)phenylboronic Acid Pinacol Ester; [4-[(tert-Butylamino)sulfonyl]phenyl]boronic Acid Pinacol Ester; 4-(tert-Butylsulfamoyl)phenylboronic Acid Pinacol Ester; B-[4-[(1,1-Dimethylethyl)amino]sulfonyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; tert-Butyl-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonyl]amine
EINECS	Contact for details

Quality Control

Our 4-(tert-Butylamino)Sulfonylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.