Description

1H-Azepine-1-Carboxylic Acid, Hexahydro-4-Hydroxy-, Phenylmethyl Ester is a high-purity, specialized organic compound belonging to the azepine class, serving as a critical building block in advanced chemical synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This intermediate is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in the fields of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex nitrogen-containing heterocycles in academic and industrial labs.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of fine chemicals and active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	1H-Azepine-1-Carboxylic Acid, Hexahydro-4-Hydroxy-, Phenylmethyl Ester
CAS No.	648418-25-1
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	Benzyl 4-hydroxyhexahydro-1H-azepine-1-carboxylate; (4-Hydroxyazepan-1-yl)(phenyl)methanone Benzyl Ester; Hexahydro-4-hydroxy-1H-azepine-1-carboxylic acid phenylmethyl ester; 4-Hydroxy-1-azepanecarboxylic Acid Benzyl Ester; 1-Benzyloxycarbonyl-4-hydroxyazepane; 1-Cbz-4-hydroxyazepane; 4-Hydroxyazepane-1-carboxylic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our 1H-Azepine-1-Carboxylic Acid, Hexahydro-4-Hydroxy-, Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.