Description

1-[(4-Fluorophenyl)Methyl]-Cyclohexanecarboxylic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its unique structural features, combining a cyclohexane carboxylic acid moiety with a fluorinated benzyl group, which imparts specific electronic and steric properties. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where the fluorinated aromatic group modifies material properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and research applications.

Basic Information

Product Name	1-[(4-Fluorophenyl)Methyl]-Cyclohexanecarboxylic Acid
CAS No.	645408-41-9
Molecular Formula	C14H17FO2
Molecular Weight	236.28 g/mol
Synonyms	4-Fluorobenzylcyclohexanecarboxylic Acid; (4-Fluorobenzyl)cyclohexanecarboxylic Acid; Cyclohexanecarboxylic acid, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)cyclohexane-1-carboxylic Acid; 1-[(4-Fluorophenyl)methyl]cyclohexanecarboxylic acid; p-Fluorobenzylcyclohexanecarboxylic Acid; 4-Fluoro-α-(cyclohexylmethyl)benzenemethanol (carboxylic acid form)
EINECS	Contact for details

Quality Control

Our production of 1-[(4-Fluorophenyl)Methyl]-Cyclohexanecarboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support applications requiring high-purity intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.