Description

2(1H)-Naphthalenone, 3,4,4A,5,6,7-Hexahydro-5,7-Dihydroxy-1,1,4A-Trimethyl- (9Ci) is a complex, partially hydrogenated naphthalenone derivative with a specific stereochemical configuration. This compound matters as a high-value chemical intermediate and research building block for synthesizing advanced molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex polycyclic structures.
• Organic Synthesis Building Block: Utilized in research laboratories for constructing intricate molecular architectures, leveraging its functionalized decalin-like core.
• Fine Chemical Production: Acts as a specialized intermediate in the manufacture of high-purity chemicals for agrochemicals, flavors, and fragrances.
• Material Science Research: Investigated as a monomer or precursor for developing advanced polymers and specialty materials with unique properties.
• Catalysis & Ligand Development: Potential use in the development of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2(1H)-Naphthalenone, 3,4,4A,5,6,7-Hexahydro-5,7-Dihydroxy-1,1,4A-Trimethyl- (9Ci)
CAS No.	643765-86-0
Molecular Formula	C13H20O3
Molecular Weight	224.30 g/mol
Synonyms	3,4,4a,5,6,7-Hexahydro-5,7-dihydroxy-1,1,4a-trimethyl-2(1H)-naphthalenone; 1,1,4a-Trimethyl-5,7-dihydroxy-3,4,4a,5,6,7-hexahydro-2H-naphthalen-2-one; 5,7-Dihydroxy-1,1,4a-trimethyl-3,4,4a,5,6,7-hexahydro-2H-naphthalen-2-one; Decahydro-5,7-dihydroxy-1,1,4a-trimethyl-2-naphthalenone; (4aS,5S,7S)-5,7-Dihydroxy-1,1,4a-trimethyl-3,4,4a,5,6,7-hexahydro-2H-naphthalen-2-one (stereospecific isomer).
EINECS	Contact for details

Quality Control

Our 2(1H)-Naphthalenone derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (specify isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.