Description

2-Amino-2',4'-Difluoroacetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a ketone functional group on a difluorinated benzene ring, makes it a versatile precursor for constructing complex heterocyclic systems. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its high purity and consistent quality are critical for ensuring reproducible results in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the creation of fluorinated molecular probes and tags for studying biological mechanisms and diagnostic applications.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and contract research organization (CRO) laboratories.

Basic Information

Product Name	2-Amino-2',4'-Difluoroacetophenone
CAS No.	643029-92-9
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	1-(2-Amino-2,4-difluorophenyl)ethanone; 2',4'-Difluoro-2-aminoacetophenone; 2-Acetylamino-1,3-difluorobenzene; 2-Amino-1-(2,4-difluorophenyl)ethan-1-one; Ethanone, 1-(2-amino-2,4-difluorophenyl)-; 2-Amino-α,2',4'-trifluoroacetophenone (common misnomer); 2-Amino-2,4-difluoroacetophenone
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2',4'-Difluoroacetophenone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the high standards required for research and commercial synthesis. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, GC, NMR, and mass spectrometry. Our quality commitment ensures reliable purity, batch-to-batch consistency, and traceability, supporting your critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.