Description

3-(5-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Benzoic Acid is a high-value, multifunctional organic building block featuring a benzoic acid core substituted with both a trifluoromethyl group and a methyl-imidazole moiety. This compound matters for its unique structural combination, offering a trifluoromethyl group for enhanced lipophilicity and metabolic stability, and an imidazole ring that can act as a ligand or a key pharmacophore. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly targeting enzymes where the imidazole ring can coordinate or interact.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the imidazole and the properties of the CF3 group.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis or metal-organic frameworks (MOFs).
• Material Science: Potential building block for advanced polymers or functional materials requiring specific electronic or binding properties.
• Chemical Biology Probes: Useful for creating tool compounds to study biological pathways due to its potential for protein binding.

Basic Information

Product Name	3-(5-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Benzoic Acid
CAS No.	641571-18-8
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	5-(Trifluoromethyl)-3-(5-methyl-1H-imidazol-1-yl)benzoic acid; 3-(5-Methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid; Benzoic acid, 3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-; 641571-18-8
EINECS	Contact for details

Quality Control

Our 3-(5-Methyl-1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Benzoic Acid is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.