Description

2-(Pyrimidin-5-Yl)Benzaldehyde is a high-purity aromatic aldehyde building block featuring a pyrimidine heterocycle, prized for its role in advanced organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a versatile building block for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its conjugated structure.
• Chemical Biology Probes: Utilized to create fluorescent tags or affinity probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	2-(Pyrimidin-5-Yl)Benzaldehyde
CAS No.	640769-71-7
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	5-Formyl-2-phenylpyrimidine; Benzaldehyde, 2-(5-pyrimidinyl)-; 2-Pyrimidin-5-yl-benzaldehyde; 5-(2-Formylphenyl)pyrimidine; (Pyrimidin-5-yl)benzaldehyde; 2-(5-Pyrimidyl)benzaldehyde; 2-(Pyrimidin-5-yl)benzenecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-(Pyrimidin-5-Yl)Benzaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.