Description

2-(2,5-Difluorophenyl)-6-Hydroxy-4(3H)-Pyrimidinone is a high-value, fluorinated pyrimidinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a difluorophenyl moiety with a pyrimidinone core, making it indispensable for constructing complex pharmacologically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in developing new herbicides, fungicides, and pesticides where the fluorinated pyrimidine structure can enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Synthesis Reagent: Employed in academic and industrial laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Biochemical Probe Development: Utilized in creating molecular probes and diagnostic agents for biological target identification and validation.

Basic Information

Product Name	2-(2,5-Difluorophenyl)-6-Hydroxy-4(3H)-Pyrimidinone
CAS No.	640271-61-0
Molecular Formula	C10H6F2N2O2
Molecular Weight	224.17 g/mol
Synonyms	6-Hydroxy-2-(2,5-difluorophenyl)-4(3H)-pyrimidinone; 2-(2,5-Difluorophenyl)-6-hydroxypyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-(2,5-difluorophenyl)-6-hydroxy-; 640271-61-0; 2,5-Difluorophenyl pyrimidinone derivative; 6-Hydroxy-2-(2,5-difluorophenyl)pyrimidin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 2-(2,5-Difluorophenyl)-6-Hydroxy-4(3H)-Pyrimidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.