Description

Phenyl(Tetrahydro-2H-Pyran-4-Yl)Methanone (CAS NO 639468-72-7) is a high-value aromatic ketone building block featuring a tetrahydropyranyl moiety, prized for its unique structural motif and reactivity. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where its scaffold can impart desirable pharmacokinetic properties. It is a critical intermediate for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed as a monomer or functional additive in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Phenyl(Tetrahydro-2H-Pyran-4-Yl)Methanone
CAS No.	639468-72-7
Molecular Formula	C₁₂H₁₄O₂
Molecular Weight	190.24 g/mol
Synonyms	4-Benzoyltetrahydropyran; (Tetrahydro-2H-pyran-4-yl)(phenyl)methanone; Phenyl(tetrahydro-2H-pyran-4-yl)methanone; 4-Phenacyltetrahydropyran; Tetrahydro-2H-pyran-4-yl phenyl ketone; 4-Benzoyloxane; 639468-72-7; Phenyl(oxan-4-yl)methanone
EINECS	Contact for details

Quality Control

Our Phenyl(Tetrahydro-2H-Pyran-4-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.