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1-[2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethanone CAS NO 638214-65-0


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CAS No.:638214-65-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-[2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethanone is a high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing complex biaryl motifs.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
  • Material Science: Precursor for organic electronic materials, including OLEDs and organic semiconductors.
  • Ligand & Catalyst Development: Serves as a starting material for creating novel ligands and organometallic catalysts.
  • Academic & Industrial R&D: Essential reagent for method development and library synthesis in medicinal chemistry.
  • Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty organic compounds.

Basic Information

Item Details
Product Name 1-[2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethanone
CAS No. 638214-65-0
Molecular Formula C15H21BO4
Molecular Weight 276.14 g/mol
Synonyms 2'-Methoxy-4'-acetylphenylboronic acid pinacol ester; 1-(2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one; 4-Acetyl-3-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acetophenone; 4-Acetyl-3-methoxybenzeneboronic acid pinacol ester; 638214-65-0; AKOS BRN-0766
EINECS Contact for details

Quality Control

Our 1-[2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0%
Assay ≥95.0%
Melting Point Contact for details
Loss on Drying ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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