Description

8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester(9Ci) CAS NO 638193-50-7 is a high-purity, functionalized bicyclic amine ester, serving as a critical advanced pharmaceutical intermediate and versatile chiral building block for complex organic synthesis. Its unique bridged structure and amino functionality make it indispensable for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors requiring high-quality, specialized intermediates.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained bicyclic scaffold.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, or auxiliaries in stereoselective transformations.
• Peptidomimetics & Bioisosteres: The 8-azabicyclo[3.2.1]octane core is a valuable scaffold for designing peptide mimics and novel bioactive molecules.
• Agrochemical Synthesis: Intermediate for developing advanced crop protection agents with specific biological activity.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester(9Ci)
CAS No.	638193-50-7
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	Ethyl 3-amino-8-azabicyclo[3.2.1]octane-8-carboxylate; 3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid ethyl ester; 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-amino-, ethyl ester; 8-N-Boc-3-amino-8-azabicyclo[3.2.1]octane (related protected form); 3-Amino-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid ethyl ester; Tropane derivative intermediate; ABOC-3-NH2 ethyl ester.
EINECS	Contact for details

Quality Control

Our production of 8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester(9Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.