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3-Chlorophenylboronic Acid, Pinacol Ester CAS NO 635305-47-4
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CAS No.:635305-47-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Chlorophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex biaryl and heterobiaryl structures.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl motifs.
- Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific chlorinated biaryl frameworks.
- Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
- Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new C-C bond-forming methodologies and creating novel compound libraries.
- Ligand Precursor: Can be utilized in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
Basic Information
| Product Name | 3-Chlorophenylboronic Acid, Pinacol Ester |
| CAS No. | 635305-47-4 |
| Molecular Formula | C12H16BClO2 |
| Molecular Weight | 238.52 g/mol |
| Synonyms | 3-Chlorophenylboronic Acid Pinacol Ester; (3-Chlorophenyl)boronic Acid Pinacol Ester; 2-(3-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-Chlorophenyl)boronate; 3-ChlorophenylBPin; 3-ClC6H4Bpin; B-(3-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
| EINECS | Contact for details |
Quality Control
Our 3-Chlorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis and maintain optimal purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥97.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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