Description

5,5-Dimethyl-2-[3-(Trifluoromethyl)Phenyl]-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, with the CAS number 635305-32-7. This chemical serves as a crucial Suzuki-Miyaura cross-coupling reagent, enabling the efficient formation of carbon-carbon bonds in complex molecule synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science & OLED Development: Employed in the creation of organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Academic & Industrial R&D: A versatile reagent in medicinal chemistry and process chemistry for exploring new chemical spaces and optimizing synthetic routes.
• Scale-up & Pilot Plant Production: Suitable for transitioning from laboratory-scale discovery to kilogram-scale production under controlled conditions.

Basic Information

Item	Detail
Product Name	5,5-Dimethyl-2-[3-(Trifluoromethyl)Phenyl]-1,3,2-Dioxaborinane
CAS No.	635305-32-7
Molecular Formula	C13H16BF3O2
Molecular Weight	272.08 g/mol
Synonyms	3-(Trifluoromethyl)phenylboronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 5,5-Dimethyl-2-(3-(trifluoromethyl)phenyl)-1,3,2-dioxaborinane; (3-(Trifluoromethyl)phenyl)boronic acid cyclic ester with neopentyl glycol; 2-(3-Trifluoromethylphenyl)-5,5-dimethyl-[1,3,2]dioxaborinane; Neopentyl glycol (3-(trifluoromethyl)phenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of our 5,5-Dimethyl-2-[3-(Trifluoromethyl)Phenyl]-1,3,2-Dioxaborinane is produced and tested under strict quality management protocols to ensure high purity, consistency, and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP-compliant development and production workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent hydrolysis and maintain reagent integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.