Description

2-(3-Methoxy-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-(1,3,2)Dioxaborolane is a high-value organoboron building block, specifically a pinacol-protected alkynyl boronic ester. This compound is critical for modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, introducing alkynyl functional groups into target molecules.
• Material Science: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Research: An essential tool in academic and industrial R&D labs for exploring new synthetic pathways and constructing complex organic compounds.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Fluorescent Probe Synthesis: Used to build molecular probes and markers for biological imaging and diagnostic applications.

Basic Information

Product Name	2-(3-Methoxy-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-(1,3,2)Dioxaborolane
CAS No.	634196-63-7
Molecular Formula	C₁₀H₁₇BO₃
Molecular Weight	196.05 g/mol
Synonyms	(3-Methoxyprop-1-yn-1-yl)boronic acid pinacol ester; Pinacol (3-Methoxyprop-1-yn-1-yl)boronate; 3-Methoxy-1-propynylboronic acid pinacol ester; 2-(3-Methoxyprop-1-ynyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Propyn-1-ylboronic acid, 3-methoxy-, 1,1-dimethylethyl ester; Alkynyl boronic ester MPPB; Pinacol alkynylboronate
EINECS	Contact for details

Quality Control

Our production of 2-(3-Methoxy-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-(1,3,2)Dioxaborolane adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure high purity and consistent performance for critical synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.