Description

2-(1-Pentynyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 634196-62-6 is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides by introducing the pentynyl moiety into target molecules.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Acts as a versatile handle for bio-conjugation and the creation of molecular probes via click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition).
• Academic & Industrial R&D: A fundamental building block for methodological development in organic synthesis and catalysis studies.
• Liquid Crystal & Polymer Precursor: Serves as a monomer or intermediate in the production of specialty polymers and liquid crystalline materials with tailored properties.

Basic Information

Product Name	2-(1-Pentynyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	634196-62-6
Molecular Formula	C₁₁H₁₉BO₂
Molecular Weight	194.08 g/mol
Synonyms	1-Pentyn-1-ylboronic acid pinacol ester; 1-Pentynylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(pent-1-yn-1-yl)-1,3,2-dioxaborolane; 2-(Pent-1-yn-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (1-pentynyl)boronate; (1-Pentynyl)boronic acid pinacol ester; 1-Pentynylboronic Acid Pinacol Ester; Pent-1-yn-1-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized by NMR (¹H, ¹³C, ¹¹B), GC/HPLC, and FTIR to confirm identity and purity. We provide comprehensive Certificates of Analysis (COA) with detailed specifications upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.