Description

2-Hydroxy-5-(Methylsulfonyl)Benzaldehyde is a versatile aromatic aldehyde derivative characterized by its hydroxyl and methylsulfonyl substituents, making it a valuable synthetic intermediate. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced material chemistry. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging its reactive aldehyde group for constructing heterocyclic systems.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-withdrawing sulfonyl group.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: The aldehyde functionality makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions to build complex biaryl structures.

Basic Information

Item	Details
Product Name	2-Hydroxy-5-(Methylsulfonyl)Benzaldehyde
CAS No.	632628-02-5
Molecular Formula	C8H8O4S
Molecular Weight	200.21 g/mol
Synonyms	5-(Methylsulfonyl)-2-hydroxybenzaldehyde; 2-Hydroxy-5-methanesulfonylbenzaldehyde; 5-Methanesulfonylsalicylaldehyde; Salicylaldehyde, 5-(methylsulfonyl)-; 2-Hydroxy-5-(methylsulfonyl)benzaldehyde; 5-Methylsulfonyl-2-hydroxybenzaldehyde; Benzaldehyde, 2-hydroxy-5-(methylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(Methylsulfonyl)Benzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.