Description

3-Formylthiophen-2-Ylboronic Acid Pinacol Ester is a high-purity, multifunctional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as Suzuki-Miyaura couplings, to construct complex heterocyclic scaffolds. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing thiophene-based heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its boronic ester functionality for structural diversification.
• Material Science Research: Employed in the creation of organic electronic materials, such as semiconductors and OLED components, where the thiophene and formyl groups contribute to desired electronic properties.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile coupling partner with aryl or vinyl halides to form biaryl or styryl compounds under palladium catalysis.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Formylthiophen-2-Ylboronic Acid Pinacol Ester
CAS No.	632325-55-4
Molecular Formula	C₁₂H₁₇BO₃S
Molecular Weight	252.14 g/mol
Synonyms	2-Formyl-3-thienylboronic acid pinacol ester; (3-Formylthiophen-2-yl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxaldehyde; 3-Formyl-2-thienylboronic acid pinacol ester; 3-Thiophenecarboxaldehyde, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol (3-formylthiophen-2-yl)boronate
EINECS	Contact for details

Quality Control

Our 3-Formylthiophen-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.