Description

2,2,2-Trifluoro-1-[3-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)Phenyl]Ethan-1-One is a high-value trifluoromethyl ketone derivative containing a pinacol boronate ester functional group. This compound is a critical building block in modern synthetic chemistry, enabling the efficient introduction of both trifluoromethyl and arylboronic ester moieties into target molecules. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used to incorporate the trifluoromethyl group, which enhances the biological activity and metabolic stability of pesticides and herbicides.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Fluorine Chemistry: An essential reagent for studying the effects of fluorine substitution on molecular properties and reactivity.
• Chemical Library Development: Employed in high-throughput and parallel synthesis to create diverse compound libraries for screening.

Basic Information

Product Name	2,2,2-Trifluoro-1-[3-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)Phenyl]Ethan-1-One
CAS No.	631909-42-7
Molecular Formula	C14H16BF3O3
Molecular Weight	300.09 g/mol
Synonyms	3'-(Trifluoroacetyl)phenylboronic acid pinacol ester; 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,2,2-trifluoroethanone; 3-Acetylphenylboronic acid pinacol ester, 3'-trifluoroacetyl; 2,2,2-Trifluoro-1-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone; 3-(Trifluoroacetyl)benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2,2,2-Trifluoro-1-[3-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)Phenyl]Ethan-1-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.