Description

Cyclopropanecarboxylic Acid, 1-(4-Iodophenyl)-, Methyl Ester is a specialized organic building block featuring a cyclopropane ring and an iodophenyl group, making it a valuable intermediate for advanced synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce cyclopropane and halogenated aromatic motifs into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring cyclopropane or halogenated aromatic components.
• Agrochemical Synthesis: Used in the discovery and production of novel herbicides, fungicides, and insecticides where the iodophenyl moiety can be further functionalized.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals, leveraging its rigid cyclopropane core.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-(4-Iodophenyl)-, Methyl Ester
CAS No.	630384-36-0
Molecular Formula	C11H11IO2
Molecular Weight	302.11 g/mol
Synonyms	Methyl 1-(4-iodophenyl)cyclopropanecarboxylate; 1-(4-Iodophenyl)cyclopropanecarboxylic Acid Methyl Ester; Methyl 1-(p-iodophenyl)cyclopropanecarboxylate; 4-Iodophenylcyclopropanecarboxylic Acid Methyl Ester; (4-Iodophenyl)cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 1-(4-iodophenyl)-, methyl ester; Methyl (4-iodophenyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-(4-Iodophenyl)-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.