Description

3-Bromo-5-Nitrobenzotrifluoride is a high-purity halogenated nitroaromatic compound featuring a trifluoromethyl group, serving as a critical building block in advanced organic synthesis. Its unique structure makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Dye and Pigment Manufacturing: Acts as a precursor for synthesizing complex, light-fast dyes and functional pigments.
• Cross-Coupling Reactions: Serves as a versatile substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.

Basic Information

Product Name	3-Bromo-5-Nitrobenzotrifluoride
CAS No.	630125-49-4
Molecular Formula	C7H3BrF3NO2
Molecular Weight	270.00 g/mol
Synonyms	1-Bromo-3-nitro-5-(trifluoromethyl)benzene; 3-Bromo-5-nitro-α,α,α-trifluorotoluene; 5-Bromo-3-nitrobenzotrifluoride; Benzene, 1-bromo-3-nitro-5-(trifluoromethyl)-; (3-Bromo-5-nitrophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Nitrobenzotrifluoride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.