Description

Pyridine-4-Boronic Acid Propanediol-1,3 Cyclic Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block for creating active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: A precursor for creating organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology & Bioconjugation: Useful for modifying biomolecules and developing probes due to its selective reactivity under mild conditions.

Basic Information

Product Name	Pyridine-4-Boronic Acid Propanediol-1,3 Cyclic Ester
CAS No.	629670-24-2
Molecular Formula	C11H14BNO3
Molecular Weight	219.05 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Pyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pyridine-4-boronic acid pinacol ester; 4-Pyridinylboronic acid pinacol ester; 4-Pyridylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pyridineboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our Pyridine-4-Boronic Acid Propanediol-1,3 Cyclic Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.