Description

8-Fluoro-3,4-dihydronaphthalen-1(2H)-one is a high-value fluorinated organic intermediate, specifically a fluorinated tetralone derivative, that serves as a critical building block in advanced synthetic chemistry. Its core value lies in the strategic incorporation of fluorine, which is essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Material Science Research: Used in the development of organic electronic materials and fluorinated polymers.
• Organic Synthesis & Methodology: A versatile substrate for studying fluorination effects and developing novel catalytic reactions (e.g., asymmetric hydrogenation, cross-coupling).
• Chemical Reference Standard: Serves as an analytical standard for quality control and metabolic studies in regulatory and R&D laboratories.

Basic Information

Product Name	8-Fluoro-3,4-dihydronaphthalen-1(2H)-one
CAS No.	628731-58-8
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	8-Fluoro-1-tetralone; 8-Fluoro-3,4-dihydro-1(2H)-naphthalenone; 8-Fluoro-α-tetralone; 1(2H)-Naphthalenone, 8-fluoro-3,4-dihydro-; 8-Fluorotetralone; 8-Fluoro-3,4-dihydronaphthalen-1-one; 8-Fluoro-1-oxotetralin
EINECS	Contact for details

Quality Control

Our 8-Fluoro-3,4-dihydronaphthalen-1(2H)-one is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.