Description

3-Bromo-4-Cyclopropylmethoxybenzaldehyde is a high-purity, versatile aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a cyclopropylmethoxy group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, where the cyclopropyl moiety can enhance biological activity and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials, including ligands for metal complexes and cores for liquid crystal molecules.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
• Chemical Derivatization: The aldehyde functional group allows for further transformations such as reductive amination, condensation, and oxidation to yield a diverse array of downstream intermediates.

Basic Information

Product Name	3-Bromo-4-Cyclopropylmethoxybenzaldehyde
CAS No.	628711-48-8
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	4-(Cyclopropylmethoxy)-3-bromobenzaldehyde; 3-Bromo-4-(cyclopropylmethoxy)benzaldehyde; Benzaldehyde, 3-bromo-4-(cyclopropylmethoxy)-; 3-Bromo-4-(cyclopropanemethoxy)benzaldehyde; 3-Bromo-4-cyclopropylmethoxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Cyclopropylmethoxybenzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, GC, NMR, and IR spectroscopy. We adhere to cGMP principles where applicable and can provide material to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.