Description

2-Thiophenecarboxaldehyde, 5-[(Aminooxy)Methyl]- (9Ci) is a specialized heterocyclic building block featuring both an aldehyde and an aminooxy functional group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of oxime-linked conjugates, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing targeted drug delivery systems, bioconjugation platforms, and novel chemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of oxime ether-linked active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation Reagent: Used for site-specific labeling and crosslinking of biomolecules (proteins, antibodies, peptides) via oxime ligation chemistry.
• Chemical Probe Development: Enables the creation of affinity-based probes for target identification and validation in drug discovery.
• Polymer & Material Science: Serves as a functional monomer or crosslinker for synthesizing smart polymers and functionalized surfaces.
• Agrochemical Research: Intermediate in the development of novel crop protection agents with specific targeting moieties.
• Diagnostic Reagent Synthesis: Used in the preparation of labeled compounds for immunoassays and imaging agents.

Basic Information

Product Name	2-Thiophenecarboxaldehyde, 5-[(Aminooxy)Methyl]- (9Ci)
CAS No.	628704-60-9
Molecular Formula	C7H7NO2S
Molecular Weight	169.20 g/mol
Synonyms	5-(Aminooxymethyl)thiophene-2-carboxaldehyde; 5-(Aminooxymethyl)-2-thiophenecarboxaldehyde; 2-Formyl-5-(aminooxymethyl)thiophene; (5-Formyl-2-thienyl)methoxyamine; Aminooxy-functionalized thiophene aldehyde; Thiophene-based oxime linker; CAS 628704-60-9
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxaldehyde, 5-[(Aminooxy)Methyl]- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.