Description

2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those requiring fluorinated and methoxylated aromatic systems.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and material science.
• Organic Electronic Materials: Useful in the synthesis of conjugated polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Facilitates the labeling and study of biological systems through bioorthogonal chemistry approaches.

Basic Information

Product Name	2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	628692-21-7
Molecular Formula	C₁₃H₁₈BFO₃
Molecular Weight	252.09 g/mol
Synonyms	2-Fluoro-4-methoxyphenylboronic acid pinacol ester; (2-Fluoro-4-methoxyphenyl)boronic acid pinacol ester; 4-Methoxy-2-fluorophenylboronic acid pinacol ester; 2-Fluoro-4-methoxybenzeneboronic acid pinacol ester; Pinacol (2-fluoro-4-methoxyphenyl)boronate; B-(2-Fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(2-fluoro-4-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.