Description

2-Pyrrolidinecarboxaldehyde, 1-(Trifluoroacetyl)-, (2S)- (9Ci) is a high-value, chiral building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical purity is critical. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in asymmetric synthesis and medicinal chemistry programs. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and meets the stringent quality requirements of the global market.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex, stereochemically defined molecules in organic and medicinal chemistry.
• Protease Inhibitor Research: Serves as a precursor in the development of inhibitors targeting various proteases.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Academic and R&D Laboratories: Utilized in chemical research for method development and exploring new synthetic pathways.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Item	Detail
Product Name	2-Pyrrolidinecarboxaldehyde, 1-(Trifluoroacetyl)-, (2S)- (9Ci)
CAS No.	628319-40-4
Molecular Formula	C7H8F3NO2
Molecular Weight	195.14 g/mol
Synonyms	(S)-1-(Trifluoroacetyl)pyrrolidine-2-carboxaldehyde; (2S)-1-(Trifluoroacetyl)-2-pyrrolidinecarboxaldehyde; N-Trifluoroacetyl-L-prolinal; L-Prolinal, N-trifluoroacetyl-; 1-(Trifluoroacetyl)-L-prolinal; (S)-N-Trifluoroacetylprolinal; (S)-2-Formyl-1-(trifluoroacetyl)pyrrolidine; (S)-1-Trifluoroacetyl-2-formylpyrrolidine
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxaldehyde, 1-(Trifluoroacetyl)-, (2S)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.