Description

2-(3-Bromo-4-Methoxyphenyl)-2-Methylpropanenitrile is a high-purity, versatile organic nitrile building block, identified by CAS number 628311-33-1. This compound is valued for its unique molecular structure, which serves as a critical intermediate in the synthesis of complex molecules. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing advanced active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its bromo and nitrile functional groups.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and advanced organic materials with specific electronic or structural properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-catalyzed cross-coupling reactions, which are fundamental to modern organic synthesis.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling the exploration of new chemical spaces and synthetic routes.

Basic Information

Product Name	2-(3-Bromo-4-Methoxyphenyl)-2-Methylpropanenitrile
CAS No.	628311-33-1
Molecular Formula	C11H12BrNO
Molecular Weight	254.12 g/mol
Synonyms	2-(3-Bromo-4-methoxyphenyl)-2-methylpropanenitrile; α-(3-Bromo-4-methoxyphenyl)isobutyronitrile; 3-Bromo-4-methoxy-α,α-dimethylbenzenepropanenitrile; 2-Methyl-2-(3-bromo-4-methoxyphenyl)propanenitrile; 2-(3-Bromo-4-methoxyphenyl)-2-methylpropionitrile; (3-Bromo-4-methoxyphenyl)(isopropyl)acetonitrile; Propanenitrile, 2-(3-bromo-4-methoxyphenyl)-2-methyl-
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-4-Methoxyphenyl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.