Description

(S)-1-Tritylpyrrolidine-2-Carbaldehyde is a high-value chiral building block and organocatalyst intermediate. This compound is critical for the synthesis of complex pharmaceutical molecules and fine chemicals due to its defined stereochemistry and reactive aldehyde functionality. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and specialty products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular drugs.
• Organocatalyst Precursor: Used in the preparation of chiral pyrrolidine-based organocatalysts for enantioselective synthesis.
• Asymmetric Synthesis: Employed in the construction of complex natural products and bioactive compounds requiring high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel, chiral pesticides and herbicides.
• Material Science: Utilized in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and chiral polymers.
• Academic & Process R&D: A valuable reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(S)-1-Tritylpyrrolidine-2-Carbaldehyde
CAS No.	628292-12-6
Molecular Formula	C24H23NO
Molecular Weight	341.45 g/mol
Synonyms	(S)-1-Triphenylmethyl-2-pyrrolidinecarboxaldehyde; (S)-N-Tritylprolinal; (S)-1-Trityl-2-formylpyrrolidine; (S)-N-Trityl-2-pyrrolidinecarboxaldehyde; (S)-N-Trityl-L-prolinal; (S)-N-Tritylproline aldehyde; (S)-1-(Triphenylmethyl)pyrrolidine-2-carbaldehyde; L-N-Tritylprolinal
EINECS	Contact for details

Quality Control

Our (S)-1-Tritylpyrrolidine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.