Description

2-{4-[3-(Dimethylamino)Propoxy]Phenyl}-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis for creating complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Industrial R&D: A fundamental reagent for synthetic organic chemists exploring new carbon-carbon bond-forming reactions and complex molecule construction.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-{4-[3-(Dimethylamino)Propoxy]Phenyl}-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	627899-90-5
Molecular Formula	C19H32BNO3
Molecular Weight	333.28 g/mol
Synonyms	4-(3-(Dimethylamino)propoxy)phenylboronic acid pinacol ester; 4-[3-(Dimethylamino)propoxy]benzeneboronic acid pinacol ester; 2-(4-(3-(Dimethylamino)propoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-(3-(Dimethylamino)propoxy)phenyl)boronic acid pinacol ester; N,N-Dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propan-1-amine
EINECS	Contact for details

Quality Control

Every batch of our 2-{4-[3-(Dimethylamino)Propoxy]Phenyl}-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard specifications are designed to meet the demanding requirements of pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.