Description

4-Fluoro-3-Cyclopropylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is a protected boronic acid derivative, offering enhanced stability and handling characteristics for advanced cross-coupling reactions. It is a critical building block for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds central to modern drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of complex molecules for potential therapeutics targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling reagents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated cyclopropyl motifs.

Basic Information

Product Name	4-Fluoro-3-Cyclopropylphenylboronic Acid Pinacol Ester
CAS No.	627526-59-4
Molecular Formula	C15H20BFO2
Molecular Weight	262.13 g/mol
Synonyms	4-Fluoro-3-cyclopropylbenzeneboronic acid pinacol ester; (4-Fluoro-3-cyclopropylphenyl)boronic acid pinacol ester; 2-(4-Fluoro-3-cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Cyclopropyl-4-fluorophenylboronic acid pinacol ester; 4-Fluoro-3-cyclopropylphenyl-Bpin; B-(4-Fluoro-3-cyclopropylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Cyclopropylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.