Description

2-(3-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific cyclopropylphenyl structures.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, including OLEDs and conductive polymers.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Research: A versatile reagent for academic and industrial R&D in cross-coupling methodology development and library synthesis for high-throughput screening.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance, flavor, and specialty chemical compounds.

Basic Information

Product Name	2-(3-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	627526-56-1
Molecular Formula	C15H21BO2
Molecular Weight	244.14 g/mol
Synonyms	3-Cyclopropylphenylboronic acid pinacol ester; (3-Cyclopropylphenyl)boronic acid pinacol ester; 3-Cyclopropylbenzeneboronic acid pinacol ester; 2-(3-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Cyclopropylphenyl-Bpin; 3-CyclophenylBPin; 1,3,2-Dioxaborolane, 2-(3-cyclopropylphenyl)-4,4,5,5-tetramethyl-
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is produced and tested under strict quality management protocols to ensure consistency and high purity for demanding synthetic applications. Our standard grade typically meets a purity specification of ≥95% (by HPLC/NMR), with rigorous control of residual solvents and metallic impurities. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing for advanced project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.