Description

4,4,5,5-Tetramethyl-2-(5,6,7,8-Tetrahydronaphthalen-2-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex organic molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides by enabling the coupling of complex aromatic fragments.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for creating advanced organic semiconductors and emissive layer materials in display and lighting technologies.
• Polymer & Material Science: Facilitates the incorporation of rigid, aromatic tetrahydronaphthalene units into specialty polymers, liquid crystals, and advanced organic frameworks.
• Cross-Coupling Reactions: Specifically designed as a stable, air-tolerant reagent for palladium-catalyzed Suzuki-Miyaura cross-coupling with various aryl/heteroaryl halides or triflates.
• Chemical Research & Development: An invaluable tool in academic and industrial R&D labs for exploring new chemical spaces and synthesizing complex molecular architectures.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(5,6,7,8-Tetrahydronaphthalen-2-Yl)-1,3,2-Dioxaborolane
CAS No.	627526-54-9
Molecular Formula	C₁₈H₂₅BO₂
Molecular Weight	284.20 g/mol
Synonyms	2-(5,6,7,8-Tetrahydronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(5,6,7,8-Tetrahydro-2-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5,6,7,8-Tetrahydro-2-naphthaleneboronic Acid Pinacol Ester; 2-(5,6,7,8-Tetrahydronaphth-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Tetralin-6-boronic Acid Pinacol Ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydronaphthalene; Pinacol (5,6,7,8-Tetrahydronaphthalen-2-yl)boronate
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(5,6,7,8-Tetrahydronaphthalen-2-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.