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2-(3-Methoxynaphthalen-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 627526-33-4


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CAS No.:627526-33-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(3-Methoxynaphthalen-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient, palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex organic molecules with precision. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in creating complex biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific naphthalene-based architectures.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for constructing advanced organic semiconductors and emissive layer materials in display and lighting technologies.
  • Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Polymer and Material Science: Facilitates the incorporation of functional naphthalene units into polymers and specialty materials to modify optical or electronic properties.
  • Academic and Industrial R&D: A vital reagent for methodological development in cross-coupling chemistry and exploring new chemical spaces in laboratory settings.

Basic Information

Product Name 2-(3-Methoxynaphthalen-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 627526-33-4
Molecular Formula C₁₇H₂₁BO₃
Molecular Weight 284.16 g/mol
Synonyms 1-(3-Methoxy-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methoxy-1-naphthaleneboronic acid pinacol ester; (3-Methoxynaphthalen-1-yl)boronic acid pinacol ester; 1-(3-Methoxynaphth-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 3-Methoxy-1-naphthylboronic acid pinacol ester; Pinacol (3-methoxy-1-naphthyl)boronate; 627526-33-4; 1-(3-Methoxynaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Quality Control

Our 2-(3-Methoxynaphthalen-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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