Description

1,3,2-Dioxaborolane, 2-[3-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- is a high-value, organoboron building block featuring a pinacol-protected boronic ester group. This compound is essential for enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing specific aryl groups into target molecules.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise conjugation is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the preparation of bioconjugates and molecular probes for diagnostic and research applications.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[3-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	627526-15-2
Molecular Formula	C16H25BO2
Molecular Weight	260.18 g/mol
Synonyms	3-tert-Butylphenylboronic acid pinacol ester; (3-(tert-Butyl)phenyl)boronic acid pinacol ester; 2-(3-tert-Butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-tert-Butylbenzeneboronic acid pinacol ester; 3-(tert-Butyl)phenylboronic acid, pinacol ester; 3-tert-Butylphenyl-Bpin; 3-t-Butylphenylboronic acid pinacol ester; 3-tert-ButylphenylBPin
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 2-[3-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.