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2-(3-Ethenylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 627525-99-9


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CAS No.:627525-99-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(3-Ethenylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and conjugated systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, crop protection agents, and organic electronic materials.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or styrenyl motifs.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for constructing electron-transport or emissive layer materials in display and lighting technologies.
  • Polymer & Material Science: Enables the incorporation of phenylvinyl groups into polymers and specialty materials to modify properties like rigidity, thermal stability, or optical characteristics.
  • Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new C-C bond-forming methodologies and complex molecule synthesis.

Basic Information

Product Name 2-(3-Ethenylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 627525-99-9
Molecular Formula C14H19BO2
Molecular Weight 230.11 g/mol
Synonyms 3-Vinylbenzeneboronic Acid Pinacol Ester; (3-Vinylphenyl)boronic Acid Pinacol Ester; 2-(3-Vinylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Vinylphenylboronic Acid Pinacol Ester; 3-Ethenylbenzeneboronic Acid Pinacol Ester; 627525-99-9; 2-(3-Ethenylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
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Quality Control

Our 2-(3-Ethenylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC/NMR). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring specific analytical data or custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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