Description

1H-Inden-1-One,3-Ethyl-2,3-Dihydro-5,6-Dimethoxy-,(3S)-(9Ci) is a high-purity chiral indanone derivative, a crucial advanced intermediate in modern organic synthesis. Its defined stereochemistry and functionalized indanone core make it a valuable building block for constructing complex molecules with high enantiomeric purity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of potential therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce the indanone scaffold with high stereoselectivity.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for application in enantioselective transformations.
• Material Science Research: Acts as a precursor for the synthesis of organic electronic materials or liquid crystals due to its rigid, planar structure and methoxy substituents.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	1H-Inden-1-One,3-Ethyl-2,3-Dihydro-5,6-Dimethoxy-,(3S)-(9Ci)
CAS No.	627518-53-0
Molecular Formula	C₁₃H₁₆O₃
Molecular Weight	220.27 g/mol
Synonyms	(3S)-3-Ethyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; (S)-3-Ethyl-5,6-dimethoxyindan-1-one; 5,6-Dimethoxy-3-ethylindan-1-one; (S)-3-Ethyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 3-Ethyl-5,6-dimethoxyindan-1-one; (S)-5,6-Dimethoxy-3-ethylindan-1-one; 1H-Inden-1-one, 3-ethyl-2,3-dihydro-5,6-dimethoxy-, (3S)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.