Description

5H-Inden-5-One,1,2,3,3A,4,7A-Hexahydro-1,3A,4,7A-Tetramethyl-,(1R,3As,4S,7Ar)-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure makes it a valuable chiral building block for constructing intricate molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for exploring new chemical entities and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, fragrances, and advanced materials requiring specific stereochemistry.
• Asymmetric Catalysis Studies: Acts as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and the synthesis of complex natural product analogs.

Basic Information

Product Name	5H-Inden-5-One,1,2,3,3A,4,7A-Hexahydro-1,3A,4,7A-Tetramethyl-,(1R,3As,4S,7Ar)-(9Ci)
CAS No.	627460-76-8
Molecular Formula	C₁₃H₂₀O
Molecular Weight	192.30 g/mol
Synonyms	(1R,3aS,4S,7aR)-1,3a,4,7a-Tetramethyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-one; (1R,3aS,4S,7aR)-1,3a,4,7a-Tetramethyloctahydro-5H-inden-5-one; Hexahydro-1,3a,4,7a-tetramethyl-5H-inden-5-one, (1R,3aS,4S,7aR)-; (1R,3aS,4S,7aR)-1,3a,4,7a-Tetramethyloctahydroinden-5-one
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under strict quality control protocols to ensure batch-to-batch consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with enantiomeric excess verified by chiral analysis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. Custom synthesis and purification to meet specific research-grade or cGMP standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be considered moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.