Description

1-Methyl-4-(4-Fluorophenyl)-Piperidine-3-Carboxylic Acid Menthyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex chiral structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry and fluorinated aromatic moieties. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and analgesic drug categories.

Application

• Key Intermediate in the synthesis of novel analgesic and neuropharmacological APIs.
• Chiral Building Block for medicinal chemistry research and process development.
• Precursor for the development of fluorinated piperidine-based drug candidates.
• Reference Standard for analytical method development and quality control in pharmaceutical manufacturing.
• Custom Synthesis starting material for contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	1-Methyl-4-(4-Fluorophenyl)-Piperidine-3-Carboxylic Acid Menthyl Ester
CAS No.	627098-37-7
Molecular Formula	C24H36FNO2
Molecular Weight	389.55 g/mol
Synonyms	Menthyl 1-Methyl-4-(4-fluorophenyl)piperidine-3-carboxylate; (-)-Menthyl 1-methyl-4-(p-fluorophenyl)-3-piperidinecarboxylate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 1-methyl-4-(4-fluorophenyl)piperidine-3-carboxylate; 4-(4-Fluorophenyl)-1-methyl-3-piperidinecarboxylic acid, (1R,2S,5R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl ester; L-Menthyl 1-methyl-4-(4-fluorophenyl)-3-piperidinecarboxylate; 627098-37-7; 1-Methyl-4-(4-fluorophenyl)piperidine-3-carboxylic acid menthyl ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(4-Fluorophenyl)-Piperidine-3-Carboxylic Acid Menthyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee supply chain reliability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.