Description

1-(4-Bromophenyl)Cyclohexanecarbonitrile is a versatile brominated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a cyclohexane ring fused to a para-brominated benzonitrile moiety, makes it a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and ligand design.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicide and pesticide candidates, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its rigid, substituted aromatic core.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	1-(4-Bromophenyl)Cyclohexanecarbonitrile
CAS No.	626603-27-8
Molecular Formula	C13H14BrN
Molecular Weight	264.16 g/mol
Synonyms	4-Bromo-α-cyclohexylbenzenecarbonitrile; (4-Bromophenyl)(cyclohexyl)acetonitrile; 1-(p-Bromophenyl)cyclohexanecarbonitrile; 4-Bromophenyl cyclohexyl ketone nitrile; p-Bromophenylcyclohexylacetonitrile; Cyclohexyl(4-bromophenyl)acetonitrile; 626603-27-8
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromophenyl)Cyclohexanecarbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment. Our quality protocols are designed to support regulatory filings and ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.