Description

{5-[(4-Acetylamino-Phenylamino)-Methylene]-3-Ethyl-4-Oxo-Thiazolidin-2-Ylidene}-Cyano-Acetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiazolidinone-based drug candidates with potential biological activity.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses, leveraging its reactive cyano and ester functional groups.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Specialty Chemical Production: Used in the manufacture of specialized dyes, pigments, or functional materials requiring its unique chromophore structure.

Basic Information

Product Name	{5-[(4-Acetylamino-Phenylamino)-Methylene]-3-Ethyl-4-Oxo-Thiazolidin-2-Ylidene}-Cyano-Acetic Acid Ethyl Ester
CAS No.	623551-18-8
Molecular Formula	C19H20N4O4S
Molecular Weight	400.45 g/mol
Synonyms	Ethyl {5-[(4-acetamidophenyl)amino]methylene-3-ethyl-4-oxo-2-thioxo-1,3-thiazolidin-2-ylidene}cyanoacetate; 2-Cyano-2-{5-[(4-acetamidophenyl)amino]methylene-3-ethyl-4-oxo-2-thioxo-1,3-thiazolidin-2-ylidene}acetic acid ethyl ester; 5-[(4-Acetylaminoanilino)methylene]-3-ethyl-4-oxo-2-thioxo-1,3-thiazolidine-2-ylidene-cyanoacetic acid ethyl ester; (5Z)-5-[(4-Acetamidoanilino)methylene]-3-ethyl-2-sulfanylidene-4-oxo-1,3-thiazolidine-2-ylidene-2-cyanoacetic acid ethyl ester; CAS 623551-18-8.
EINECS	Contact for details

Quality Control

Our {5-[(4-Acetylamino-Phenylamino)-Methylene]-3-Ethyl-4-Oxo-Thiazolidin-2-Ylidene}-Cyano-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with exacting R&D and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.