Description

2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde is a high-value, functionalized benzaldehyde derivative featuring a protected boronic acid group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in many modern drugs and agrochemicals.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with complex aromatic backbones.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating organic semiconductors and emissive materials in display technologies.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer and Material Science: Building block for advanced polymers, covalent organic frameworks (COFs), and other functional materials.
• Chemical Research & Development: A versatile reagent for academic and industrial research in synthetic methodology development.

Basic Information

Product Name	2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde
CAS No.	620595-36-0
Molecular Formula	C13H17BO4
Molecular Weight	248.09 g/mol
Synonyms	5-Formyl-2-hydroxyphenylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-hydroxybenzaldehyde; 2-Hydroxy-5-(pinacolatoboryl)benzaldehyde; 5-(Pinacolboron)salicylaldehyde; Salicylaldehyde-5-boronic acid pinacol ester; 5-Borono-2-hydroxybenzaldehyde pinacol ester; 5-(Pinacolatoboron)salicylaldehyde; 2-Hydroxy-5-(pinacolboron)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.