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4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Phenyl]-1,3,2-Dioxaborolane CAS NO 620595-02-0
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CAS No.:620595-02-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Phenyl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity, making it a preferred reagent for constructing complex molecular architectures under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug discovery.
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
- Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating advanced organic semiconductors and charge-transport materials used in display and lighting technologies.
- Polymer & Materials Science: Enables the synthesis of specialty polymers, liquid crystals, and metal-organic frameworks (MOFs) with tailored properties.
- Academic & Process R&D: A valuable reagent for methodological development in cross-coupling chemistry and for scaling up novel synthetic routes.
- Fine Chemical Production: Employed in the manufacture of complex fragrance, flavor, and dye intermediates where precise aromatic coupling is required.
Basic Information
| Product Name | 4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Phenyl]-1,3,2-Dioxaborolane |
| CAS No. | 620595-02-0 |
| Molecular Formula | C20H30B2O4 |
| Molecular Weight | 356.07 g/mol |
| Synonyms | 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylboronic acid pinacol ester; 1,4-Phenylenebis(pinacolboronate); p-Phenylenebis(boronic acid pinacol ester); 1,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; p-Bis(pinacolboron)benzene; 1,4-Bis(pinacolatoboryl)benzene; BDBP |
| EINECS | Contact for details |
Quality Control
Our production of 4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Phenyl]-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC-MS, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are provided with every shipment, and we support compliance with REACH, TSCA, and other global regulatory frameworks.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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