Description

1-(2-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemistry researchers, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of proprietary APIs for clinical trials.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for cutting-edge organic synthesis and pharmacology research.

Basic Information

Item	Details
Product Name	1-(2-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	618101-80-7
Molecular Formula	C18H13FN2O3
Molecular Weight	324.31 g/mol
Synonyms	1-(2-Fluorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-pyrazole-4-carboxaldehyde; 1-(2-Fluorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-pyrazole-4-carbaldehyde; 1-(2-Fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-4-carbaldehyde; 6-[4-Formyl-1-(2-fluorophenyl)-1H-pyrazol-3-yl]-2,3-dihydro-1,4-benzodioxine; 618101-80-7 (CAS Registry Number); Fluorophenyl dihydrobenzodioxinyl pyrazole carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client requirements or regulatory standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.