Description

1-(4-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazole-dioxin hybrid structure. This compound is of significant commercial value for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile pyrazole core and fluorophenyl moiety.
• Process Development: Serves as a critical intermediate for scaling up the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology: Employed as a probe or precursor in the development of enzyme inhibitors or receptor modulators.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	618101-64-7
Molecular Formula	C18H13FN2O3
Molecular Weight	324.31 g/mol
Synonyms	1-(4-Fluorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-pyrazole-4-carboxaldehyde; 4-Fluoro-1,3-dihydro-2H-benzodioxin-6-yl-1H-pyrazole-4-carbaldehyde; 618101-64-7; 1H-Pyrazole-4-carboxaldehyde, 1-(4-fluorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-; 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-3-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)-1H-Pyrazole-4-Carbaldehyde adheres to stringent quality management systems to ensure batch-to-batch consistency and purity suitable for pharmaceutical research. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.