Description

3-(4-Bromophenyl)-1-(3-Chloro-4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is a high-purity, multi-substituted pyrazole derivative serving as a critical advanced pharmaceutical intermediate. Its complex halogenated aromatic structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new generation pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds due to its reactive aldehyde and pyrazole functional groups.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	3-(4-Bromophenyl)-1-(3-Chloro-4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	618098-83-2
Molecular Formula	C16H9BrClFN2O
Molecular Weight	379.61 g/mol
Synonyms	4-Bromo-α-(3-chloro-4-fluorophenyl)-1H-pyrazole-3-acetaldehyde; 1-(3-Chloro-4-fluorophenyl)-3-(4-bromophenyl)-1H-pyrazole-4-carboxaldehyde; 3-(4-Bromophenyl)-1-(3-chloro-4-fluorophenyl)-4-formylpyrazole; 3-(p-Bromophenyl)-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbaldehyde; 618098-83-2; Pyrazole-4-carbaldehyde, 3-(4-bromophenyl)-1-(3-chloro-4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-1-(3-Chloro-4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.