Description

1-(2,4-Difluorophenyl)-3-p-Tolyl-1H-Pyrazole-4-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazole-carbaldehyde core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides, leveraging the biological activity of the difluorophenyl and pyrazole motifs.
• Organic Synthesis & Chemical Research: Used in academic and industrial R&D for constructing complex heterocyclic libraries and exploring new reaction pathways in medicinal chemistry.
• Material Science Precursor: Potential application in the synthesis of specialized ligands for catalysis or functional organic materials.

Basic Information

Product Name	1-(2,4-Difluorophenyl)-3-p-Tolyl-1H-Pyrazole-4-Carbaldehyde
CAS No.	618098-75-2
Molecular Formula	C17H12F2N2O
Molecular Weight	298.29 g/mol
Synonyms	1-(2,4-Difluorophenyl)-3-(4-methylphenyl)-1H-pyrazole-4-carboxaldehyde; 3-p-Tolyl-1-(2,4-difluorophenyl)-1H-pyrazole-4-carbaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1-(2,4-difluorophenyl)-3-(4-methylphenyl)-; 618098-75-2; 4-Formyl-1-(2,4-difluorophenyl)-3-p-tolylpyrazole; 1-(2,4-Difluorophenyl)-3-(p-tolyl)-1H-pyrazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 1-(2,4-Difluorophenyl)-3-p-Tolyl-1H-Pyrazole-4-Carbaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.