Description

(3,5-Bis(Trifluoromethyl)Phenylethynyl)& CAS NO 618092-28-7 is a high-value, multi-functional aromatic building block featuring a phenylethynyl linker flanked by two trifluoromethyl groups. This compound is prized for its unique electronic properties and chemical stability, making it a critical intermediate in advanced material synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology, where the trifluoromethyl groups enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its lipophilicity and resistance to degradation.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling and polymerization reactions.
• Advanced Material Science: Integral in the production of organic semiconductors, liquid crystals, and high-performance polymers for electronics and optics due to its rigid, conjugated structure.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science R&D for exploring structure-activity relationships (SAR) and new molecular entities.
• Fluorinated Compound Libraries: Used in combinatorial chemistry to create libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	(3,5-Bis(Trifluoromethyl)Phenylethynyl)& CAS NO 618092-28-7
CAS No.	618092-28-7
Molecular Formula	C11H3F6
Molecular Weight	264.13 g/mol
Synonyms	1-Ethynyl-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)phenylacetylene; 3,5-Bis(trifluoromethyl)ethynylbenzene; (3,5-Bis(trifluoromethyl)phenyl)acetylene; 3,5-Di(trifluoromethyl)phenylacetylene; 3,5-Bis(trifluoromethyl)benzen-1-ylacetylene; 3,5-Bis(trifluoromethyl)phenylethyne
EINECS	Contact for details

Quality Control

Every batch of (3,5-Bis(Trifluoromethyl)Phenylethynyl)& CAS NO 618092-28-7 undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.