Description

5-(Trifluoromethyl)-1-(2-Methoxyphenyl)-1H-Pyrazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its pyrazole core with trifluoromethyl and methoxyphenyl substituents. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the pyrazole and trifluoromethyl groups.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the creation of diverse compound libraries for high-throughput screening.
• Material Science Research: Investigated for potential applications in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	5-(Trifluoromethyl)-1-(2-Methoxyphenyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	618070-64-7
Molecular Formula	C12H9F3N2O3
Molecular Weight	286.21 g/mol
Synonyms	1-(2-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; 5-(Trifluoromethyl)-1-(o-methoxyphenyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 5-(trifluoromethyl)-1-(2-methoxyphenyl)-; 618070-64-7; 5-Trifluoromethyl-1-(2-methoxyphenyl)pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-(2-Methoxyphenyl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.