Description

(3-Fluorothiophen-2-Yl)Methanol is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive hydroxymethyl group and a fluorine-substituted thiophene ring, enabling precise molecular modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated conjugated polymers and organic semiconductors for electronic and optoelectronic applications.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its bioisosteric properties.
• Custom Synthesis and Scale-Up: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis for client-specific projects.

Basic Information

Product Name	(3-Fluorothiophen-2-Yl)Methanol
CAS No.	614729-70-3
Molecular Formula	C5H5FOS
Molecular Weight	132.16 g/mol
Synonyms	2-(Hydroxymethyl)-3-fluorothiophene; 3-Fluoro-2-thiophenemethanol; (3-Fluoro-2-thienyl)methanol; 3-Fluorothiophene-2-methanol; 3-Fluoro-2-thiophenecarbinol; 3-Fluoro-2-thienylcarbinol; 3-Fluorothien-2-ylmethanol
EINECS	Contact for details

Quality Control

Our (3-Fluorothiophen-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.